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affair
aggravation
annoyance
barrier
bind
bother
botheration
brain-teaser
brainteaser
bug
bugaboo
bugbear
business
can of worms
case
catch
challenge
cliff-hanger
closed book
complaint
complication
complications
concern
condition
contretemps
conundrum
corner
count
delinquent
difficult
difficulty
dilemma
disadvantage
disagreement
discomfort
disease
disobedient
disorder
dispute
disputed point
disturbed
double bind
doubt
downside
drawback
embarrassment
enigma
example
exercise
exercises
facer
fix
fixation
fly in the ointment
glitch
gordian knot
grievance
handful
hassle
hazard
headache
hitch
hold-up
hot water
how-do-you-do
illustration
inconvenience
infection
intractable
intransigent
intricacy
issue
jam
job
kink
liability
logjam
lookout
maladjusted
matter
mess
mire
misery
mystery
nuisance
obscurity
obstacle
obstruction
pain
peeve
peril
perplexity
pest
pickle
pitfall
plague
point at issue
poser
predicament
puzzle
puzzler
quandary
query
question
recalcitrant
refractory
riddle
rub
scrape
secret
setback
sixty-four thousand dollar question
snag
spot
squeeze
stickler
struggle
stumbling block
stumper
subject
subjects
sum
syndrome
task
teaser
the rub
theme
thing
tight spot
topic
topics
toughie
trap
trial
trouble
troublesome
twister
uncontrollable
ungovernable
unmanageable
unruly
vexation
vexed question
woe
worriment
worry
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